We changed it throughout the document and title of the manuscript to wireless communication radiation, thank you. A good time to call: BlueCross. In summary, the article can be printed, but the title is very ambitious! 4G and 5G per se do not use polling. The year 2012 involved many significant scientific events and discoveries, including the first orbital rendezvous by a commercial spacecraft, the discovery of a particle highly similar to the long-sought Higgs boson, and the near-eradication of guinea worm disease.A total of 72 successful orbital spaceflights occurred in 2012, and the year also saw numerous In another study, rats exposed to 945 MHz (base station frequency) at 0.367 mW/cm2 for 7 h/day, over 8 days, demonstrated low glutathione levels and increased malondialdehyde and superoxide dismutase enzyme activity, hallmarks for oxidative stress [83]. Reviewer #11: In this work authors summarize current state of knowledge about the harmful effects of Radiofrequency radiation (RFR), with special focus on those that could possibly enhance the possibility of being infected by COVID-19. Miller AB, Sears ME, Morgan LL, Davis DL, Hardell L, Oremus M, et al. There is a huge amount of work in the western world having tested the bioactivity of the RF and ELF parameters of complex RF signals which is much more reliable than the mistranslated Russian studies. For a specific municipality it depends on the antenna density, what network protocols are used, as, for example, 2G, 3G, 4G, 5G, Wi-Fi, WiMAX (Worldwide Interoperability for Microwave Access), DECT (Digital European Cordless Telecommunications), and RADAR (Radio Detection and Ranging). (1992) found that certain frequencies (55 GHz; 73 GHz) caused pronounced arrhythmia. [28] This indicates that altered or deficient repair of DNA damage contributes to the formation of gliomas. RFR (radiofrequency radiation) from ubiquitous radiowave transmitters, including antennas, base stations, smart meters, mobile phones, routers, satellites, and other wireless devices currently in use superimposes and yields an additive average power density at a given location that typically fluctuates greatly over time. We included the world literature in English and Russian reports translated to English, on radio frequencies from 600 MHz to 90 GHz, the carrier wave spectrum of WCR (2G to 5G inclusive), with particular emphasis on nonthermal, low power densities (<1 mW/cm2), and long-term exposures. Environmental Health Perspectives, 115 (1): 14. For example, on p.9 they state: This evidence presented here does not claim causation. Yet, on p.10 they state: We conclude that RFR and, in particular, 5G, which involves densification of 4G, has exacerbated the COVID-19 pandemic by The absorption of microwaves by water molecules is no different than the absorption of infrared (heat). Retrieved August 9, 2019, from https://www.gaspforair.org/gasp/gedc/pdf/E-CigSmoke.pdf, Gottlieb, S., & Abernethy, A. FCC96-326; ET Docket No. and Shafirkin, A.V., 2010. Specifically, the evidence does not confirm causation.. But as this paper shows, there is multiple evidence that there are adverse effects on tissue systems and their physiology, that have nothing to do with the heating effects of RFR. While the authors claim no conflict of interest they acknowledged that this work was supported by the Mobile & Wireless Forum (MWF). (2018, February 21). Moreover, we are dealing with a pandemic, and many COVID-19 researchers are citing non-peer-reviewed papers to present evidence as soon as it is available that might help us understand more and/or mitigate the pandemic. So I highly support that this paper be published as soon as possible, so that its thesis can be studied and be debated by a much wider scientific audience, and further testing and research can be done, to further investigate these findings and projections for our survival in our collective future, Reviewer #10: - Page 2, introduction section, last paragraph. Outpatient medical services. In addition, patients with morbid obesity may have restricted lung tidal volumes, exacerbating the clinical effect of lung disease caused by Sars-CoV-2. [6], Some studies of diet and vitamin supplementation appear to point out that dietary N-nitroso compounds may affect the risk of both childhood and adult brain tumors. The latest finalized 5G standard, Release 16, is codified in the 3GPP published Technical Report TR 21.916 and may be downloaded from the 3GPP server at https://www.3gpp.org/ftp/Specs/archive/21_series/21.916/ (3GGP, 2020).. [42] Wang et al. Authors should also specify if these exposures are below or above the international limits. Using a radiofrequency power meter to measure ambient levels from 100 MHz 8 GHz in downtown San Francisco, California, recently we found an average power density of 0.0002 mW/cm2, which is approximately 2x10E10 times greater than the natural background. According to the CDC, early disease symptoms may include sore throat, headache, fever, cough, chills, among others. Other investigators have shown diminished T-lymphocytes or suppressed immune function in animals exposed to WCR. The new infrastructure will service the new 5G devices, including 5G mobile phones, routers, computers, tablets, self-driving vehicles, machine-to-machine communications, and the Internet of Things (IoT). Testing could also include real-life exposures to multiple toxins (chemical and biological) [141], because multiple toxins may lead to synergistic effects. Telehealth services available. It is unlikely that any microwave EMF does not contain such components, even in the form of on/off for energy saving reasons. Thus, there are no universally accepted safety standards for wireless communication radiation exposure. Moreover there is no microwave generator that is not turned on and off for energy saving reasons and this represents additional pulsations. By comparison, Soviet researchers found in the 1970s that radiofrequency radiation can damage the immune system of animals. The Bioinitiative Report (https://bioinitiative.org/research-summaries) written in 2012 by 14 scientists, public health, and policy experts, and updated in 2020, summarizes hundreds of peer-reviewed scientific papers documenting evidence of non-thermal effects from exposures less than or equal to 1mW/cm2. Mordachev VI. Cite regions that had a 5G rollout but were not hit by the pandemic, and please provide explanations for such exemptions. Therefore, we cannot estimate accurately the values of these signal parameters including ELF components or predict their variability over time. We are puzzled as to why we originally measured 50 Hz with the previous DECT phone base. 4) Measurements were averaged over the entire range of an antenna panel covering essentially 180 of azimuth angle. So I think overally, mobility of people, meeting of families during holidays and inproper precautions have much larger effect on the pandemia than RFR exposure. COVID-19 outbreaks soon followed in other areas where 5G had also been at least partially implemented, including South Korea, Northern Italy, New York City, Seattle, and Southern California. The authors completely ignored the wi-fi pulsations before my comments. These guidelines were established in 1996 [131], are antiquated, and are not safety standards. Associations between COVID-19 Incidence Rates and the Exposure to PM2.5 and NO2: A Nationwide Observational Study in Italy. The plans are for 5G to blanket the world, leaving no place, without this new exposure to this Microwave and Milliwave radiation, and potentially effecting all life on earth, with the exception of beings that live in lead-lined shelters, or Faraday cages. Pulsed radio-frequency radiation such as WCR exhibits substantially different bioeffects, both qualitatively and quantitatively (generally more pronounced) compared to continuous waves at similar time-averaged power densities [33-36]. Even within a single household, exposure to RFR can vary dramatically depending upon a persons relative distance to wireless routers, tablets, smart meters, mobile phones, Bluetooth devices, and other wireless products. Pathophysioloy. Family Medicine 1 Provider. Provide another link to this document. Glutathione deficiency has been proposed as the most likely cause of serious manifestations in COVID-19 [72]. [2], Symptoms of gliomas depend on which part of the central nervous system is affected. We cannot schedule these appointments online. Under these conditions, the 3-fold increase in rate of synthesis of LDLr in the hepatomas was closely matched by increases in the level of its mRNA.In the case of fibroblasts, a 10-fold increase in translational efficiency was required to explain the 30-fold change in rate of synthesis of LDLr. Cell biochemistry and biophysics. For many, treatment consists of just surgery, or even "watchful waiting" (waiting to see when an intervention is justified due to tumour progression). One wonders how many people died of those cool technologies, from cancer or other illnesses, before their dangers were finally recognized and removed from the market. 11. The reproducibility of bioeffects of WCR exposure has sometimes been difficult due to failure to report and/or control all of these parameters. The next steps involve a complex process leading to the viral penetration through the host cell plasma membrane into the cytosol [Mercer, J., Schelhaas, M. and Helenius, A. Toxic chemicals may be present in e-liquids (vape juice) or could be created as the liquid is turned into a gas. Both the very young and the very old populations are the most vulnerable to adverse effects from RFR exposure. We did not make an attempt to weigh the evidence. Electromagnetic Fields, Such as Those from Mobile Phones, Alter Regional Cerebral Blood Flow and Sleep and Waking EEG. We included this text in the Discussion Section: This evidence suggests that RFR may have worsened the COVID-19 pandemic by weakening the host and exacerbating COVID-19 disease. Get Labcorp at Walgreens reviews, rating, hours, phone number, directions and more. Authors should indicate in the table the most relevant and specific reference(s) for each listed point. Guidelines for evaluating the environmental effects of radiofrequency radiation. To achieve higher data throughput QAM can be set to a larger constellation size to increase spectral efficiency. Mobile communications and health of population: the risk assessment, social and ethical problems. Garaj-Vrhovac et al. (2016) Comments on environmental impact of radiofrequency fields from mobile phone base stations, Critical Reviews in Environmental Science and Technology, 46:9, 885-903. iterate through digits of a number javascript, Register Here. Humana. [65] Whilst, evidence is uncertain on whether there are long term neurocognitive side effects associated with chemoradiotherapy. Low-level WCR from devices, including mobile telephony base antennas, wireless network protocols utilized for the local networking of devices and internet access, trademarked as Wi-Fi (officially IEEE 802.11b Direct Sequence protocol; IEEE, Institute of Electrical and Electronic Engineers) by the Wi-Fi alliance, and mobile phones, among others, may disrupt regulation of numerous physiological functions. Specifically, the evidence does not confirm causation.. In other words, ELF pulsations or other modulations are apparently not part of the 5G protocol itself, or else this may be proprietary and not in the public domain. https://doi.org/10.1007/s12013-010-9150-8 ] It is hypothesized that intracellular water thus affected by absorption of GHz radiation affects the hydration of protein molecules in organisms that may alter protein structure and rates of biochemical reactions (Betskii and Lebedeva, 2004). Evidence for a connection between COVID-19 and exposure to radiofrequency radiation from wireless communications including 5G. Furthermore, because the received power varies from location to location due to obstacles in the propagation path and anisotropy in the antennas radiation pattern, these measurements must be performed at all locations of interest. - Background section. Semin5 studied the effect of weak RFR on the stability of DNAs secondary structure in vitro. 2018, 37 (2): 66-75. https://doi.org/10.1080/15368378.2018.1463246, Bektas H, Dasdag S, Effect of Radiofrequencies Emitted from Mobile Phones and Wi-F on Pregnancy. Szmigielski S. Reaction of the Immune System to Low-level RF/MW Exposures. Johns Hopkins Healthcare (EHP/PP) COMMERCIAL. Page 7, right, lines 3-5. In May 2020, Mordachev [4] reported a statistically significant correlation between the intensity of radiofrequency radiation and the mortality from SARS-CoV-2 in 31 countries throughout the world. Pakhomov and Murphy Paper: Review of Russian Research. ", "Consensus on the role of human cytomegalovirus in glioblastoma", "A comprehensive next generation sequencing-based virome assessment in brain tissue suggests no major virus - tumor association", "Absence of Cytomegalovirus in Glioblastoma and Other High-grade Gliomas by Real-time PCR, Immunohistochemistry, and, "Animal viruses, bacteria, and cancer: a brief commentary", "The epidemiology of glioma in adults: a "state of the science" review", "Women's Safety and Health Issues at Work: Job Area: Agriculture", National Institute for Occupational Safety and Health, "Gliomas and farm pesticide exposure in women: the Upper Midwest Health Study", "The Upper Midwest Health Study: a case-control study of pesticide applicators and risk of glioma", "Association between DNA repair gene polymorphisms and risk of glioma: a systematic review and meta-analysis", "DNA damage, homology-directed repair, and DNA methylation", "Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island", "MGMT, GATA6, CD81, DR4, and CASP8 gene promoter methylation in glioblastoma", "O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients", "miR-181d: a predictive glioblastoma biomarker that downregulates MGMT expression", "Role of ERCC1 promoter hypermethylation in drug resistance to cisplatin in human gliomas", "The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer", "Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2", "Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6", "Disruption of Brca2 increases the spontaneous mutation rate in vivo: synergism with ionizing radiation", "Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas", "CpG island methylator phenotype in colorectal cancer", "The CpG island methylator phenotype (CIMP) in colorectal cancer", "Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198", "IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas", "Malignant glioma: genetics and biology of a grave matter", "The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary", "Disparities in Brain Cancer in the United States: A Literature Review of Gliomas", "Management of glioblastoma: State of the art and future directions", "Oncolytic Viruses for Malignant Glioma: On the Verge of Success? Retrieved August 14, 2019, from https://www.kcur.org/post/if-you-thought-vaping-was-safe-kansas-researchers-have-bad-news#stream/0, Mayo Clinic. [94]. Johns Hopkins EHP, Priority Partners MCO, and Johns Hopkins US Family Health Plan, please refer to the provider manuals or contact your network manager. Phone. COVID-19 can cause insufficient oxygen levels (hypoxia) that have been seen in up to 80% of intensive care unit (ICU) patients [9] exhibiting respiratory distress. The 3GPP is publishing separate specifications for each frequency range designated as Frequency Range 1 (FR 1) and Frequency Range 2 (FR 2). Sierra Health and Life, P.O. These types of radiation do not exist without pulsations/ELF components (see Pirard and Vatovez for recordings of such signals). The DECT pulsations are not known to be 50 Hz but 100 Hz and 200 Hz (see Pedersen 1997). of network providers without logging in. Retrieved August 9, 2019, from https://www.fda.gov/news-events/fda-voices-perspectives-fda-leadership-and-experts/understanding-health-impact-and-dangers-smoke-and-vapor, Harvard T.H. All appeal requests should be submitted in writing. Makar V, Logani M, Szabo I, Ziskin M. Effect of Millimeter Waves on Cyclophosphamide Induced Suppression of T Cell Functions. The sentence should be reformulated. However, our RF meter was insensitive to 5G frequencies above 8 GHz. However, as we wrote in other responses in this Second Rebuttal, there is evidence for nonthermal bioeffects of continuous microwaves, unmodulated, for example, on water and the hydration of biomolecules that can subsequently affect their structure and function, and lead to microwave bioeffects, as well as evidence for cardiac arrhythmias due to exposure to continuous millimeter waves. [41] One of these mutations (mostly in IDH1) occurs in about 80% of low grade gliomas and secondary high-grade gliomas. We added the following material to the manuscript that starts at the bottom of page 3 - 4. Reviewer #10: - Background section. Reviewer #11: Authors have responded to all of my questions and notes. Change to: at non-thermal power densities (< 1 mW/cm2). Therefore, the table should be more informative for the readers for evaluation of the situation. An accurate determination of a base stations radiated RF power at a certain location is only possible through well-defined measurement protocols, such as the FCC Publication No. Typically, any tumour presenting as above WHO grade I (i.e. Pakhomov et al., 1998, who wrote a review of bioeffects and reviewed the Russian paper, indicated no modulations were used, and we had already cited and provided a reference to this review paper, too. The prevalence of such blood changes upon exposure to RFR in the human population has not yet been determined. Moustafa YM, Moustafa RM, Belacy A, Abou-El-Ela SH, Ali FM. Reviewer #8: This paper delves into a facet of CoVid-19 and the evolving use of the widespread release of 5G into the environment, and the relationship between the two. In 2013, Havas observed erythrocyte aggregation including rouleaux (rolls of stacked red blood cells) in live peripheral blood samples following 10 minute human exposure to a 2.4 GHz cordless phone. 4) The biggest shortcoming of this study is the failure of the authors to create realistic scenarios of users actually using the 5G network. Number of Covered Lives Johns Hopkins Advantage MD (ERA required to receive EFT) NPI -(R) M: 52189: Johns Hopkins Healthcare (EHP/PP) Provider ID - (O) M, H: 52123: Johns Hopkins Healthcare (USFHP) Provider ID - (O) M, H: LMCHP: Leon Medical Centers Health Plans (EFT required to receive ERA) If indeed, all of the systems effected by CoVid-19 are also potentially weakened or. Baranski S. Effect of Chronic Microwave Irradiation on the Blood Forming System of Guinea Pigs and Rabbits. Bikdeli B, Madhavan MV, Jimenez D, Chuich T, Dreyfus I, Driggin E, Nigoghossian C, et al. Unfortunately, there is no scientific data about whether these similarities create a synergistic effect or not. Second and third waves of the pandemic disseminated widely throughout communities with and without RFR, as would be expected.. 5G is a protocol that will use high frequency bands of the electromagnetic spectrum in the vast radiofrequency range from 600 MHz to nearly 100 GHz, which includes millimeter waves (>20 GHz), in addition to the currently used 3G (third generation) and 4G (fourth generation) long term evolution (LTE) microwave bands. Learn more here. 38(1): 32-47, 2019. The Precautionary Principle in Environmental Science. A bibliography of over 3700 references on the reported biological effects in the world scientific literature was published in 1972 (revised 1976) by the US Naval Medical Research Institute [27,28]. 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