Since the causes of leg hair loss are so numerous, its important to take all your symptoms into account to get an accurate diagnosis. By itself, its usually not a sign of an underlying health condition. There are actually some factors that can cause you to bruise more easily: Bruising occurs when the blood vessels beneath the skin are ruptured. For hair loss caused by atherosclerosis and PAD, undergoing an angioplasty, atherectomy, or stent placement may increase the blood flow in your legs. Heart failure: Could a low sodium diet sometimes do more harm than good? Treatment options vary depending on cancer type, but they may include medication, chemotherapy, and surgery. Before your appointment, it can be helpful to write down a list of symptoms youre experiencing and the medications youre taking so that you are prepared for the visit. , Hair Research Society of India, April-June 2014, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154156/, [2] Schramm, Kristofer, and Paul J. Rochon. They can also vary from child to child, as not all children with leukemia show the symptoms listed above. According to the National Cancer Institute in the United States, it is the most common type of cancer in children and teens, accounting for 1 out of 3 cancers affecting this age group. https://www.uptodate.com/contents/search. By using our website, you consent to our use of cookies. WebA bruise is a noticeable mark on the skin that generally resolves over time. Lack of appetite, stomachache, and weight loss. This is called traction alopecia. All rights reserved. and endo. Gibson LE (expert opinion). (n.d.). When Leukemia cells cause swelling in the liver, kidneys, or spleen, these organs can press against the stomach. A leukemia diagnosis can be frightening, but the survival rates continue to improve. Noble, J. M., & Patterson, M. C. (2020). Were committed to answering your questions and improving your quality of life. Children often fall or get bumped when learning to walk or while playing. Complications from the following may give rise to thrombocytopenia: Approximately 510% of pregnant people and those who have recently given birth develop gestational thrombocytopenia. I'm concerned that i might have low testosterone. These side effects may go away during treatment as your body adjusts to the medicine. information and will only use or disclose that information as set forth in our notice of A family history of balding on your mother's or father's side, Certain medical conditions, such as diabetes and lupus. DOI: aad.org/public/diseases/hair-and-scalp-problems/alopecia-areata, aad.org/public/diseases/hair-and-scalp-problems/hair-loss#overview, americanhairloss.org/hair_loss_treatment/, cdc.gov/dhdsp/data_statistics/fact_sheets/fs_pad.htm, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, What Causes Hair Loss in Teenagers, and How to Treat It. can i ask dr. about lupus? Like other types of alopecia, its thought to be hereditary. Hair loss. Briggs JK. WebAnterolateral leg alopecia refers to hair loss on your legs thats primarily located on the front and outer sides. For example, PAD can cause anterolateral leg alopecia, as can genetics and rubbing the legs together too often. MedicineNet does not provide medical advice, diagnosis or treatment. i'm losing hope. This is when youll notice signs like toenails that grow slowly, wounds that take longer than usual to heal, and hair loss on your lower legs. Terms of Use. Although celiac disease most frequently triggers gastrointestinal distress, it may also trigger an autoimmune rash. Older adults bruise more easily due to thinning of the skin and less cushioning from fat. It affects more males than females, though not by a large margin. Sepsis is a life threatening complication of an infection. Evaluation and diagnosis of hair loss. Some exceptions are leg-specific conditions, such as PAD in your legs or friction from the clothing you wear. To diagnose unexplained bruising in you or your child, your doctor will: Your doctor can use blood test results to assess: In some cases, your doctor may take a sample of bone marrow to test if they suspect you may have a type of cancer based on the results of blood testing. According to one older study, people with close family members who bruise easily may also experience frequent bruising. Gender Differences in Peripheral Vascular Disease. Seminars in Interventional Radiology, Thieme Medical Publishers, March 2018, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886764/. Minor cases of hair loss on your legs could be temporarily based on stress, life changes, and other acute conditions. Many early symptoms of leukemia in children are also symptoms of common, less serious childhood illnesses. Theyll check your medical history and likely run blood tests to see if your hair loss might be caused by nutritional deficiencies, lack of thyroid hormone, or other conditions. Wear comfortable clothing and drink plenty of water beforehand. A stent placement uses the same procedure as an angioplasty but with the added step of leaving a small mesh stent in the artery to keep it propped open. Waloters Kluwer; 2019. Graves' disease is an autoimmune disorder that affects the thyroid, a gland in the neck that produces hormones and affects the body's metabolism. You can learn more about how we ensure our content is accurate and current by reading our. An atherectomy involves using a tiny blade to remove plaque from a narrowed artery. Please ensure email address is accurate as all important information regarding treatment, schedules will be sent here. "Weak collagen causes the blood vessel walls to break more easily, causing easy bruising," Kouri says. With early cirrhosis, there are often no symptoms. Although some people may not view losing hair on the calves, shins, or legs as a problem, it is important to know that it may indicate a larger health issue. Advertising revenue supports our not-for-profit mission. They can include flu-like illness, fatigue, lack of appetite, headaches, and frequent infections. The blood may be so thick that circulation slows through small vessels in the brain. Accessed Jan. 31, 2020. Bleeding disorders. However, while lifestyle changes are important and can help slow the course of PAD, advanced PAD requires treatment to help restore blood flow and improve a patients quality of life. As a person ages, they become more susceptible to bruising. If you see your primary care physician due to, , you may be referred to a vascular doctor for additional testing to diagnose or rule out peripheral artery disease. large purple stretch marks. In some cases, a child may also experience more obvious health problems. If you are concerned about your symptoms, please contact your doctor. Leukemia is a form of cancer that affects the body's bone marrow, blood-producing tissues and lymphatic system. The People affected by this condition may find themselves asking, Why am I losing hair on my lower legs? They may reach out to a dermatologist, believing that losing hair on the calves could be a skin issue and nothing else. All lymph sites swollen for about13 months as well as skin nodules, accompanied by bruising, hair loss, extreme weight loss, fatigue, itching mostly a? Because the lower extremities lack adequate amounts of oxygen-rich blood, they cannot function as they should. WebThough many forms of leukemia exist, unexplained, rapid weight loss and easy bruising may are potential symptoms of all types. This can result in bruising easily on your legs or other areas of your body. Sometimes, bruising without an injury could be a sign of a serious underlying medical condition like diabetes, a blood clotting disorder, or an autoimmune disease. Advertisement. Maturitas. There are different types of childhood leukemia. When these cells grow abnormally, leukemia occurs. Additional symptoms of leukemia may include chills i'm concerned about low t. What can cause fatigue, strange bruising, and hair loss? Vitamin K deficiency bleeding: Facts about vitamin K deficiency and bleeding. You have a lot of symptoms - some physical, some mental. what blood workup have you done. Make sure your house is lit well so you can see where youre walking and whats around you or on the floor. Hair loss occurs when individual hairs break away from the follicles and the follicles fail to produce new hairs. This condition isnt caused by one particular health issue, instead, it is a catchall term for any sort of hair loss on the legs. We avoid using tertiary references. , which most commonly impacts the arteries in the legs. Keep furniture out of areas where you walk so youre less likely to bump into it. There are many other medical conditions that also can be associated with your symptoms and signs. This, in turn, can result in the regrowth of hair on your legs, but it also may not. A damaged liver affects the bodys ability to form clots and stop bleeding. With PAD, the arteries become hardened when plaque attaches to the artery walls, narrowing the passageway. Our vascular doctors are experts at diagnosing PAD, and they will be able to tell whether or not the test indicates restricted blood flow in your peripheral arteries. Is the ketogenic diet right for autoimmune conditions? Skip the wait times! Some studies show an association between smoking and baldness in men. A Decrease font size. This site complies with the HONcode standard for trustworthy health information: verify here. Learn about how to get, A bruise, or contusion, occurs when an area of skin has suffered trauma. Laryngeal Cancer: A persistent cough or hoarse-sounding voice are possible signs. When the liver lacks healthy tissue, which is needed for protein production, immune system function, proper digestion, blood health and energy, unexplained weight loss and easy bruising may occur. Vitamin K plays an important role in blood clotting, so a vitamin K deficiency can also contribute to bruising. Other people at risk of developing scurvy include older adults and people who drink a lot of alcohol. There are many reasons why teenagers may experience hair loss. The following are a few of the possible conditions that may cause random bruising to appear on the legs. One study estimates that about 35 percent of older men have this condition. With alopecia areata, for example, the immune system confuses hair cells as foreign invaders and attacks them. A Reset font size. Hims vs. Hair loss can occur on your legs just as it can on your head, and, similarly, genetics can play a role in this issue. Also talk to your doctor if you notice sudden or patchy hair loss or more than usual hair loss when combing or washing your or your child's hair. Last medically reviewed on March 10, 2022, What are the possible causes of random bruising? Some MS symptoms can be treated with medications. MayoClinic.com suggests prompt medical guidance at the onset of symptoms. For women who are experiencing a receding hairline (frontal fibrosing alopecia), talk with your doctor about early treatment to avoid significant permanent baldness. You may opt-out of email communications at any time by clicking on The exact cause of leg hair loss should be diagnosed by your doctor. Unexplained bruising on the legs can occur in both adults and children due to a variety of factors, including injury, age, an underlying health condition, or even things like medication. All rights reserved. Healthline Media does not provide medical advice, diagnosis, or treatment. Be gentle with your hair. People deficient in vitamin K may also bruise more often. March 26, 2020. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Signs and symptoms of multiple myeloma. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. This, in turn, can result in the regrowth of hair on your legs, but it also may not. Your email address will not be published. The doctor will perform various tests and assessments before making a diagnosis. Applying ice and elevating your leg may help. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Be sure to follow your doctors instructions regarding treatment. Mayo Clinic, Nov. 25, 2019. Last basic blood panels were ok. i do have reynauds, new hair loss, now feel sick after sun, bruises, joint aches/fatigue. A blood clot is a clump of blood that has formed in deeper tissue or within a blood vessel and is rarely visible. If a child seems to be in pain and complains that their bones or joints are sore or achy, this can indicate childhood leukemia. Other factors may cause unexplained leg bruising. HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. Mayo Clinic does not endorse companies or products. Find out which type may be causing your symptoms, treatment, and. If you have other signs of PAD, you should seek out further evaluation from a medical professional. Malki L, et al. The result may be a feeling of fullness or discomfort, a lack of appetite, and subsequent weight loss. (2016). Wear comfortable clothing and drink plenty of water beforehand. 44 yr female, pain in right hand, head, face shoulder & neck. Gender Differences in Peripheral Vascular Disease., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886764/. One of these cancers is multiple myeloma. , which may be a sign of PAD, but it appears to affect men more than women. include diabetes, poor circulation, thyroid conditions, fungal infection, folliculitis in severe stages, hormone changes, and pituitary gland disorders. Childhood leukemia represents about 24.9% of all new childhood cancer cases. However, if your leg hair loss is widespread and long-lasting, it may be time to see your doctor. A Increase font size. This content does not have an English version. (2018). Early detection and diagnosis of symptoms like. Doctors call this collection of cells a chloroma or a granulocytic sarcoma, and it is very rare. that are mononuclear (with a single nucleus) "Mono" and "kissing Nutrafol Review: Does It Really Work for Hair Loss? confirm my parent(s) or personal representative consent my intention to have a treatment A bruise often forms while the outer layer of skin is still intact and it changes the color of the visible layers of skin. This can include things like domestic abuse, child abuse, and elder abuse. Most of the time, bruising occurs when a person bumps into things, falls, or injures themselves in another way. If you have further questions about hair regrowth after treatment, consult one of our vascular doctors. Both men and women can experience anterolateral leg alopecia, which may be a sign of PAD, but it appears to affect men more than women. You should also tell your doctor whether or not you are experiencing additional symptoms of PAD, such as slowed toenail growth, skin discoloration, and cramping in the legs while walking or jogging. Hair loss. Is exercise more effective than medication for depression and anxiety? Certain medications that help treat rheumatoid arthritis, including corticosteroids, may also contribute to random bruising. Symptoms of scurvy include bleeding issues that may lead to bruising. Your doctor may need to do some testing to make an accurate diagnosis. The bruising and bleeding that characterize leukemia can also cause tiny spots on the skin called petechiae to appear. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Centers for Disease Control and Prevention (CDC), http://blog.arthritis.org/living-with-arthritis/serious-arthritis-symptoms/, https://liverfoundation.org/for-patients/about-the-liver/diseases-of-the-liver/alcohol-related-liver-disease/, https://www.aafp.org/afp/2008/0415/p1117.html, https://www.sciencedirect.com/science/article/pii/S0019483216300074, https://ghr.nlm.nih.gov/condition/bernard-soulier-syndrome, https://www.cancer.gov/about-cancer/treatment/side-effects/bleeding-bruising, https://www.hog.org/handbook/article/3/33/bruises, https://www.leukaemiacare.org.uk/support-and-information/latest-from-leukaemia-care/blog/spotting-the-difference-bruising-in-leukaemia-vs-ordinary-bruising/, https://bcmj.org/articles/more-just-bruise-recognizing-child-physical-abuse, https://ashpublications.org/blood/article/130/21/2271/36666/Thrombocytopenia-in-pregnancy, https://ghr.nlm.nih.gov/condition/factor-v-deficiency#definition, https://jamanetwork.com/journals/jama/fullarticle/1377924, https://rarediseases.org/rare-diseases/immune-thrombocytopenia/, https://orthoinfo.aaos.org/en/diseases--conditions/muscle-contusion-bruise, https://www.aafp.org/afp/2016/0215/p279.html, https://bestpractice.bmj.com/topics/en-gb/632, https://www.cancer.org/cancer/multiple-myeloma/detection-diagnosis-staging/signs-symptoms.html, https://www.nia.nih.gov/health/skin-care-and-aging, https://liverfoundation.org/for-patients/about-the-liver/the-progression-of-liver-disease/, https://www.nhlbi.nih.gov/health-topics/thrombocytopenia, https://www.cdc.gov/sepsis/what-is-sepsis.html, https://www.cdc.gov/ncbddd/vitamink/facts.html, https://www.cdc.gov/ncbddd/vwd/facts.html, Cardiovascular health: Insomnia linked to greater risk of heart attack. At USA Vascular Centers, our trusted vascular doctors can conduct two tests to determine if your anterolateral leg alopecia could be caused by PAD. However, while lifestyle changes are important and can help slow the course of PAD, advanced PAD requires treatment to help restore blood flow and improve a patients quality of life. depression and mood swings. Make a donation. Allscripts EPSi. The symptoms of acute leukemia often appear quickly, and they may be more noticeable. For further assistance, please contact us. Additional symptoms of leukemia may include chills or fever, physical weakness, red splotches on the skin, easy bleeding from cuts or wounds, excessive perspiration and bone pain. Without enough vitamin C in the body, random bruising can occur. Hereditary hair loss with age is the most common cause of baldness. Also, tumors from other types of cancers are more likely to put pressure on the superior vena cava and lead to facial swelling. When leukemia develops, the abnormal cells can collect close to the surface of the bones or inside joints. Phrenic Nerve damage and paralyzed diaphragm: Anyone else have this? When the hair follicles dont receive enough nutrition, the hair will stop growing. If you dont get enough vitamin C Hair loss occurs when new hair doesn't replace the hair that has fallen out. In most cases, the, People affected by this condition may find themselves asking, , They may reach out to a dermatologist, believing that. The doctor may also perform other diagnostic tests, including blood tests, to rule out any serious underlying causes of bruising. When the hair follicles dont receive enough nutrition, the hair will stop growing. Bruising may occur for no apparent reason on the legs. Many of the symptoms are common and can indicate a range of illnesses. nausea. Fatigue. As many as 35% of men1 are thought to develop this condition over their lifetime. Diseases That Cause Skin Discoloration & Weight Loss, 4 Possible Causes of Bleeding From the Breast, United States Department of Health and Human Services: Graves' Disease Information, National Digestive Diseases Information Clearinghouse: Cirrhosis Information. Meanwhile, the specific cause of bruising in children can sometimes be difficult to determine. Sepsis is a life threatening complication of an infection. Hair loss of the legs is called anterolateral leg alopecia. Some people bruise more easily than others. Read more below to learn why you may be experiencing random Bruises may also take longer to heal in older adults. This could be the case, but its important to check for PAD regardless of your gender. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. For potential or actual medical emergencies, immediately call 911 or your local emergency service. This could be the case, but its important to check for PAD regardless of your gender. Confirm by entering The links above will provide you with more detailed information on these medical conditions to help you inform yourself about the causes and available treatments for these conditions. Here are our top picks for shampoos for thinning hair, whether it's for hair loss, thinned hair strands, or both. Keeps is one of many options for hair loss treatment, with some advantages and considerations. Heart failure: Could a low sodium diet sometimes do more harm than good? 304 Wainwright Dr. These outpatient procedures do not require a hospital stay you can recover in the comfort of your own home. Early treatment of a receding hairline (frontal fibrosing alopecia) might help avoid significant permanent baldness. Graves' disease is treatable, generally through synthetic hormones, iodine treatments or, in some cases, surgery. As many as 35% of men, are thought to develop this condition over their lifetime. Since the causes of leg hair loss are so numerous, its important to take all your symptoms into account to get an accurate diagnosis. Find out how to protect yourself from potential drug interactions. 2. Signs and symptoms of hair loss may include: See your doctor if you are distressed by persistent hair loss in you or your child and want to pursue treatment. Cold caps and scalp cooling systems. There are several treatment options for thrombocytopenia. Anemia would explain all your symptoms except the itching, which probably is manifesting because your skin is cold and dry (which are symptoms of Anemia). Steroid use can lead to. For example, in adults, bruising can occur more easily as we age due to thinning of the skin. Review/update the Can diet help improve depression symptoms? Dr. Shiloh was awarded a fellowship from the Society of Interventional Radiology, a prestigious distinction that only the top 10% of doctors in his field have earned. Let's look at symptoms and treatments. Prevalence of Hair Loss on Legs for Men and Women. include protected health information. (n.d.). However, if the bruising is the result of taking specific medications or supplements, stopping them could eliminate further bruising. A ruptured spleen can be a life threatening condition and requires immediate attention. Vitamin C: Vitamin C is important for many reasons, one being wound healing. USA Vascular Centers offers various minimally invasive, During an angioplasty, the doctor threads a catheter through a blood vessel and inflates a tiny balloon, compressing the plaque and widening the artery. Interventions for female pattern hair loss. Cancer stat facts: Childhood leukemia (ages 019). WebI have been getting random unexplained bruises on my legs/thighs for the last year or so. Vocal changes can also be caused by polyps or hypothyroidism. Sepsis. According to the National Digestive Diseases Information Clearinghouse, approximately 5 percent of people with cirrhosis later develop liver cancer. These can all signal a lack of adequate blood flow to your legs. Chemotherapy and you: Support for people with cancer. Siah TW, et al. This is called superior vena cava syndrome and rarely occurs in cases of leukemia. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. If a medication or supplement is causing the bruising, your doctor may have you stop taking it or prescribe an alternative, if possible. Changes to your tongue, such as it swelling and turning red as a strawberry. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. If a parent or caregiver notices any of the symptoms above, it is best to take the child to a doctor as soon as possible. You may be eager to minimize the appearance or tenderness of a bruise. and sometimes females. Learn more about these serious fractures, how theyre treated, and what to expect. Because the lower extremities lack adequate amounts of oxygen-rich blood, they cannot function as they should. can help prevent the progression of the disease. Leukemia affects the blood cells, most often, the white blood cells. MedTerms medical dictionary is the medical terminology for MedicineNet.com. Bruising often occurs when blood vessels beneath the skin incur damage. Sex. MS is treated with disease-modifying therapies. (2018). , making lifestyle changes such as quitting smoking and beginning an exercise plan can help keep the disease from advancing quickly. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Achilles Tendon Rupture: Symptoms to Look For, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, Ruptured Spleen: Symptoms and Treatment in Adults and Children. Celiac disease occurs when gluten causes excessive gut inflammation, which may cause the following symptoms: Anemia. The cause of this condition is unknown, but it primarily affects older women. You can learn more about how we ensure our content is accurate and current by reading our. Northbrook IL-60062 Some hair loss conditions, such as alopecia areata, are caused by a faulty immune system. 5. You most likely just bruise more easily than others, and therefore dont remember the injury or bump that caused the bruise. You may also need to take medication to reduce the chance of blood clots. This constellation of symptoms should be evaluated as soon as possible to rule out any complicating condition that may be prolonging your recovery or Why do i have fatigue, hair loss on legs, depressed, crying? Your symptoms can be due to a wide range of medical causes. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. (2016). Some of these disorders include: Other symptoms that people with blood disorders may experience include: Treatment options for bleeding disorders vary but may involve platelet transfusions, clotting factors, or medications to help with clotting. There are two types of leukemia, and each can be chronic or acute. doc help? JAMA Dermatology. Accessed Jan. 31, 2020. Office of Patient Education. Ask your doctor about medications and supplements you take that might cause hair loss. A stent placement uses the same procedure as an angioplasty but with the added step of leaving a small mesh stent in the artery to keep it propped open. A child with this type of cancer will have a lack of platelets that help prevent bleeding. You can also suffer from hair loss if your body is deficient in certain nutrients, such as iron, vitamin D, or zinc. The symptoms of this condition include thrombocytopenia, which lowers blood platelet counts and leads to bleeding and bruising. Some autoimmune conditions, such as rheumatoid arthritis and lupus, may cause unexplained bruising. If you find that you or your childs bruises occur frequently, are large, and dont improve after a week or two, see your doctor. Mayo Clinic; 2019. Other symptoms include: skin that bruises easily. Depending on the suspected cause, your doctor may also refer you to a dermatologist that specializes in skin and hair disorders. Platelets or other clotting factors arent functioning properly. Most people do not notice symptoms of PAD until atherosclerosis is advanced, causing significantly restricted blood flow to the legs, feet, and ankles. If baldness runs in the family, you could also experience hair loss on other parts of your body, such as your legs. There arent enough platelets or other clotting factors being produced. Hims and Keeps offer helpful hair loss treatments for men but is one better than the other? Several cancers that affect the blood cells can also cause random bruising. This damage results in symptoms that may include numbness, weakness, vertigo, paralysis, and involuntary muscle contractions. Bruising is the most common injury sustained by children who have been subject to physical abuse. If you're being treated with chemotherapy, ask your doctor about a cooling cap. Accessed Feb. 3, 2020. Early detection and diagnosis of symptoms like leg pain and hair loss on the legs can help prevent the progression of the disease. A variety of conditions can cause permanent or temporary hair loss, including hormonal changes due to pregnancy, childbirth, menopause and thyroid problems. Our website services, content, and products are for informational purposes only. Unexplained leg bruising can be due to liver disease, nutritional deficiencies, autoimmune conditions, and other disorders. This occurs when leukemia cells collect in the blood, causing the blood to thicken. It can be alarming to see unexplained bruises on your legs or your childs legs, particularly if you dont recall an incident that couldve caused them. Methods of treatment are advancing and survival rates for some forms of the disease continue to improve. Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. In the type of patchy hair loss known as alopecia areata, hair loss occurs suddenly and usually starts with one or more circular bald patches that may overlap. Leukemia is a type of cancer of the blood cells in which the growth and development of the blood cells are abnormal. The median diagnosis is at 6 years of age. Please call us us to continue scheduling your appointment. The progression of liver disease. Even without detectable symptoms, you may have developed a condition known as peripheral artery disease (PAD), which most commonly impacts the arteries in the legs.